However, the reviewers found no scientific evidence for a significant association between endoxifen and clinical outcomes.
The primary outcome was the percentage of time that the international normalized ratio INR was in the therapeutic range from day 4 or 5 through day 28 of therapy.
Stinchcombe et al summarized the evidence presented and stated that the results of crizotinib in molecularly selected patients with advanced NSCLC whose tumor cells had a novel fusion protein involving ALK reinforces the importance of understanding molecular heterogeneity in this patient population.
It is believed that suboptimal response to an anti-platelet regimen pharmacodynamic effect may be associated with cardiovascular, cerebrovascular, and peripheral arterial events.
At 4 weeks, the mean percentage of time in the therapeutic range was
The boxed warning states that the effectiveness of Plavix is dependent on its activation to an active metabolite by the cytochrome P CYP system, principally CYP2C
These analyses have investigated the association between these single nucleotide polymorphisms and haplotypes of these polymorphisms and asthma-related phenotypes such as lung function, airways hyperresponsiveness, and response to a bronchodilator, and have suggested that certain regions of the gene may be associated with different phenotypes.
Kimmel, et al.